Abstract
Peroxisomes are single membrane-bound organelles that are ubiquitous in eukaryotic cells. Plant peroxisomes are differentiated into several types, including glyoxysomes and leaf peroxisomes. Their functions are adapted in response to environmental and developmental cues, and tightly regulated by multiple factors involved in peroxisome biogenesis, such as protein transport. Since peroxisomes does not have own genome unlike mitochondria and chloroplasts, the enzymes participated in peroxisomal functions are encoded in nuclear genome and are transported into peroxisomes after protein synthesis in the cytosol. However, precise machineries of peroxisomal protein transport have not been clarified. To identify the factors regulating peroxisome biogenesis, we have screened the aberrant peroxisome morphology (apm) mutants. We have already identified the novel plant-specific factor, APM9, which is required for peroxisomal protein transport via protein-protein interaction with AAA-ATPase complex. In this presentation, we will report another apm mutant, apm10.
