Abstract
Enuresis is more common and treatment resistance for enuresis is higher in children with attention deficit hyperactivity disorder (ADHD) than in children showing typically normal development. Previous reports have described that medical therapy for ADHD effectively treats enuresis in these children. Case 1: A 7-year-old boy received guanfacine (1 mg) to reduce distraction, and the nocturnal enuresis rate reduced from more than 90 % to 0 % within a week. Case 2: A 13-year-old girl received guanfacine (1 mg) and methylphenidate (18 mg) to manage carelessness, and the nocturnal enuresis rate reduced from 100 % to approximately 30 % within a week. Midway awakening decreased in Case 1 and sleep onset and awakening improved in Case 2. We consider that improvement in sleep quality is associated with improvement in enuresis. Guanfacine is a useful treatment option in children with ADHD presenting with enuresis.
