Treatment duration for syphilis in pregnant Japanese women by 2021

Abstract

Aim: We evaluated the effect of oral aminobenzylpenicillin (OA) for syphilis during pregnancy in terms of treatment duration.

Methods: In August 2021, we requested 2,146 obstetrical facilities to provide information on syphilis treatment in pregnant women.

Results: There were 45 pregnant women who received OA for active syphilis. Among these women, the median duration of OA treatment was 12 weeks, and four (9%) had been prescribed OA for more than 24 weeks.

Conclusion: It takes a long time to adequately treat syphilis with OA during pregnancy.