Abstract
Two overlapping cases of Sjögren's syndrome and sarcoidosis are reported.
Case 1, A73-year old woman with a 11-year history of primary Sjögren's syndrome, was admitted to our hospital for evaluation of fever and abnormal shadow on chest X-ray film. Laboratory data revealed ACE 39.4. Chest CT scans showed bilateral hilar lymphadenopathy with thickening of the pertbronchovascular interstinum. A transbronchial lung biopsy was performed revealing numerous epithelioid cell granuloma consistent with sarcoidosis.
Case 2, A41-year old man was admitted to our hospital for evaluation of fever and abnormal shadow on chest X-ray film. Laboratory data revealed positive anti SS-A antibody. Chest CT scans showed bilateral hilar and mediastinal lymphadenopathy with thickening of the pertbronchovascular interstinum. A transbronchial lung biopsy was performed revealing epithelioid cell granuloma consistent with sarcoidosis. A diagnosis of Sjögren's syndrome was confirmed by positive Schirmer's test and sialography, which showed an abnormal pooling with an apple tree-like pattern in the parotid gland.
