A Case of Sarcoidosis with Symptomatic Muscle Involvements and Sjögren's Syndrome

Abstract

A 54-year old woman was admitted to a local hospital with severe muscle pain and solid masses of both legs. She was transfered to our hospital for further examination, because sarcoidosis was suspected by the histological examination of muscle biopsy. A chest X-ray film revealed bilateral hilar lymphadenopathy and diffuse reticulonodular opacities in both lungs. Histological examination of transbronchial lung biopsy specimens showed non-caseous epithelioid cell granulomas, and on these bases a diagnosis of sarcoidosis was made. Her clinical conditions improved, and solid masses subsided after the administration of prednisolone. She had the symptoms of eye and mouth dryness for 2 years, and the diagnosis of Sjögren's syndrome was made by laboratory findings and sialography. This was a rare case of sarcoidosis with symptomatic muscle Involvements and Sjögren's syndrome.