Abstract
A 40 year old woman with uveitis was diagnosed as having sarcoidosis by the Daniels' lymphnode biopsy. Fibrotic change of the lung had gradually progressed and corticosteroid therapy was considered. But no corticosteroids were prescribed through long term observation over 20 years as a result of the patient's strong objection. Cystic change, thickness around the bronchovascular bundle and volume loss of the lung progressed little by little, and the patient finally developed chronic respiratory failure requiring home oxygen therapy. She died of complication of pulmonary aspergillosis at the age of 62. Pulmonary aspergillosis is well known as a complication of advanced pulmonary sarcoidosis for patients who have undergone corticosteroid therapy. But this case indicates to us that pulmonary aspergillosis is an important complication even for patients who have not undergone corticosteroid therapy.
