Abstract
We treated a 67-year-old female ostomy patient suffering from a condition in which her skin barriers peeled off earlier than expected. Her trouble appeared to be due to a hydrophobic-based suppository,which had dissolved. In order to verify this speculation,we conducted a comparative study to clinically examine the influence of hydrophobic-and hydrophilic-based suppositories on the adhesiveness of skin barriers. Results showed that the hydrophobic-based suppository,when dissolved,spreads along the border face between the skin and the skin barrier to weaken adhesiveness,whereas the hydrophilic-based suppository,in its dissolved state,is absorbed by the skin barrier. These findings clarified the fact that the hydrophobic ingredient in dissolved suppositories,when these are administered to ostomy patients,exerts a negative inflence upon the adherence of the skin barrier.