Abstract
We examined how the selection of skin barriers in proportion to the drainage was obtained for clinical use. Digestive juice was carried in 9 kinds of prototypes,taking the development of skin barriers with high buffer action into consideration,and pH was measured on a time-dependent basis. Ten grams of the main raw material of skin barriers was stirred in distilled water and digestine juice until it was dissolved,and the pH was measured. When the SIS (styrene-isoprene-styrene block copolymer) consists of 25％ or less,the SIS rate in the hydrophobic polymer gives to skin barriers an excellent buffer action. However,it is necessary to consider the constituents of the prototype,to consider that the buffer action for gastric juice is weak,and that it can not be used in a gastric fistula. Although karaya gum,which is the main raw material of skin barriers,is excellent for buffer action in alkaline environment,mixtures of CMC are necessary when buffer action in an acidic environment is necessary.
