Abstract
【Objective】 We assessed the pancreas marginal donor criteria of the University of Minnesota (UM), the University of Pittsburgh (UP), the EXPAND study, and the Japanese Society for Pancreas and Islet Transplantation Association (JPITA) in our sixteen donor series.
【Design】Retrospective case series
【Methods】Marginal donor was defined as follows: (1) ＞45years old, (2) hemodynamically unstable at harvest using high-dose dopamine or more than 2 vasopressors in UP criteria; (1) ＞45years old, (2) cerebro-cardiovascular disease death in UM criteria; (1) 50 to 60 years old, (2) body mass index (BMI) of 30 to 34 kg/m2 in EXPAND criteria; (1) ＞60 years old, (2) BMI ＞30 kg/m2 in JPITA criteria.
【Results】 The marginal donor was defined in fifteen cases (94%) for UP and/or UM criteria; in eight cases (50%) for EXPAND criteria; and in two cases (13%) for JPITA criteria. Primary nonfunction and pancreas graft removal was not found in our series for thrombosis, pancreatitis and acute rejection. Actual pancreas graft survival was 86% with a mean follow-up of 37months.
【Conclusion】Pancreas graft survival from marginal donor in our series was acceptable. Utilization of pancreata from marginal donors may expand the availability of pancreas grafts for transplantation.
