2020 Volume 55 Issue 3 Pages 245-260
As of December 31, 2019, a total of 10,038 liver transplants had been performed in 69 institutions in Japan. There were 595 deceased donor transplants (592 from heart-beating donors and 3 from non-heart-beating donors) and 9,443 living-donor transplants. The annual total of liver transplants in 2019 was 395 (88 deceased donor transplants and 307 living-donor transplants). The most frequent indication was cholestatic disease, followed by hepatocellular disease and neoplastic disease. As for hepatocellular disease in 2019, alcoholic cirrhosis and non-alcoholic steatohepatitis were the most common. Patient survival following transplantation from heart-beating donors (592 transplants: 1-year 89.6%, 3-year 86.1%, 5-year 82.9%, 10-year 74.9%, 15-year 64.4%, 20-year 49.5%) was similar to that from living-donors (9,443 transplants: 1-year 85.4%, 3-year 81.5%, 5-year 79.0%, 10-year 73.9%, 15-year 69.3%, 20-year 65.8%, 25-year 63.1%, 30-year 58.2%). Graft survival was very much the same as patient survival (heart-beating donor: 1-year 89.1%, 3-year 86.1%, 5-year 82.8%, 10-year 74.8%, 15-year 64.3%, 20-year 49.5%; living-donor: 1-year 84.7%, 3-year 80.5%, 5-year 77.9%, 10-year 72.3%, 15-year 67.2%, 20-year 63.4%, 25-year 60.4%, 30-year 55.1%). Survival data are reported according to age and sex of recipient, indication, graft type, age and sex of donor, ABO-compatibility, and other factors.
