A case of pure red cell aplasia due to parvovirus B19 infection about 4 years after ABO-incompatible kidney transplantation

Abstract

A woman underwent ABO-incompatible living kidney transplantation in her fifties. She was taking three immunosuppressants, tacrolimus, everolimus and methylprednisolone. Three years and eleven months after the transplantation, her blood test showed pancytopenia and liver dysfunction (AST: 136 IU/L, ALT: 91 U/L). As a result of scrutiny, we diagnosed PVB19 infection and treated it with a dose reduction of immunosuppressant and blood transfusion. The treatment was successful without IVIG administration, and there has been no recurrence.