Japanese Journal of Transplantation
Online ISSN : 2188-0034
Print ISSN : 0578-7947
ISSN-L : 0578-7947
Downsizing cadaveric lung transplantation
SUGIMOTO SeiichiroHaruki CHOSHIShin TANAKAMegumi ISHIHARAKohei HASHIMOTOKen SUZAWAKazuhiko SHIENKentaroh MIYOSHIHiromasa YAMAMOTOMikio OKAZAKIShinichi TOYOOKA
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2023 Volume 58 Issue Supplement Pages s143_2

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Abstract

BACKGROUND: Since donation after cardiac death is not approved for lung transplantation (LT) in Japan, maximizing the utilization of extended criteria donor lungs is essential to solve donor shortage. Among various techniques in LT, we describe our experience of downsizing cadaveric LT (DCLT).METHODS: We retrospectively reviewed 17 recipients who underwent DCLT among 218 recipients of LT at our institution.RESULTS: DCLT was performed for 10 female and 7 male patients ranging in age from 9 to 55 years. The diagnoses included interstitial pneumonia (n = 9), diffuse panbronchiolitis (n = 2), pulmonary hypertension (n = 2) and others (n = 4). The median waiting time was 467 (53-1029) days. Bilateral LT was performed after uni-lobectomy (n = 11) or multi-lobectomy (n = 6). The cause of lobectomy was pneumonia (n = 8), oversized graft (n = 5), and trauma (n = 4). Bronchial stenosis was observed in one of 4 bronchial stumps, whereas no complication developed in 13 lobar-to-lobar bronchial anastomoses. The 5- and 10-year overall survival rates were 78.7% and 78.7%, respectively.CONCLUSION: DCLT provided favorable long-term outcomes and appears to be a viable option for selected patients.

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この記事はクリエイティブ・コモンズ [表示 - 非営利 - 改変禁止 4.0 国際]ライセンスの下に提供されています。
https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ja
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