2021 Volume 16 Issue 2 Pages 38-41
A 52-year-old woman visited our department with headache and nausea. Brain magnetic resonance imaging showed cerebral venous sinus thrombosis (CVST), but an investigation of thrombotic predisposition was negative. The patient was a nonsmoker, but the patient’s urinary cotinine level was found to be increased. The patient's husband was a current smoker, thus, we diagnosed the patient as CVST due to second-hand smoke. We advised her husband to quit smoking, and the patient has shown no recurrence to date. CVST is a central neurological disorder that occurs based on thrombotic tendency and may accompany serious symptoms such as cerebral hemorrhage, cerebral infarction, and convulsions. However, smoking has not been demonstrated to be a risk factor for CVST, although meta-analyses have shown that smoking tends to increase the risk of CVST. To our knowledge, this is the first report to associate CVST with second-hand smoke. Further studies are necessary to accumulate similar cases.
