Japanese Journal of Stroke
Online ISSN : 1883-1923
Print ISSN : 0912-0726
ISSN-L : 0912-0726
Review
Gene therapy for cerebral infarct: Focusing on ex vivo gene therapy
Takao YasuharaNaoki TajiriFeifei WangTanefumi BabaTomohito KadotaLeung HanbaiJudith Thomas TayraYoichiro KikuchiKenichiro MuraokaMasahiro KamedaTakashi AgariAkihiko KondoTomohito HishikawaShigeki OnoYasuyuki MiyoshiKoji TokunagaIsao Date
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2009 Volume 31 Issue 6 Pages 420-424

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Abstract
New therapeutic strategies are explored for patients suffering from cerebral infarct. Gene therapy is one of the hopeful strategies and we have studied ex vivo gene therapy for stroke using animal models of cerebral infarct over a decade. In this review, we describe encapsulated cell transplantation using neurotrophic factor-producing cells and neurotrophic factor-producing neural stem/progenitor cells for cerebral infarct model of animals. Furthermore, the perspectives of gene therapy for cerebral infarct are reviewed.
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© 2009 The Japan Stroke Society
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