Abstract
Physostigmine is used to treat emission loss. We report on a 31-year-old male who used physostigmine for artificial ejaculation after a cervical spinal cord injury. He suffered an acute intracerebral hemorrhage after a subcutaneous physostigmine injection and artificial ejaculation. We examined him carefully using MRI, digital subtraction angiography, and so on, but there were no malignancies, aneurysms, or any other vascular abnormalities to induce the hemorrhage. Physostigmine is known as a safe drug to stimulate the parasympathetic system. Physostigmine injection and autonomic hyperreflexia due to artificial ejaculation may increase blood pressure and the risk of intracerebral hemorrhage in spinal men.
