Abstract
Our goal was to clarify the relationship between blood pressure (BP) and functional outcome at discharge in patients with intracerebral hemorrhage (ICH) by using the dataset of the Fukuoka Stroke Registry (FSR). We selected the patients with ICH who were admitted to the hospitals within 24 hours of onset between June 2007 and May 2008. A good functional outcome was defined as a modified Rankin Scale score of 2 or less at discharge. BPs were recorded at admission, 6 hours after admission, 24 hours after onset, and 7 days after onset, and multivariable analysis was performed to compare the BPs and baseline characteristics of the patients with and without good functional outcomes. Furthermore, the BPs of patients with ICH during antithrombotic therapy were compared of those with and without good outcomes. The multivariable analysis indicated that in all ICH patients, the systolic BP at 24 hours after onset was associated significantly with the outcome at discharge (p<0.05). Good functional outcomes were predicted for patients when their systolic BPs were less than 135 mmHg at 24 hours after onset. In the patients with ICH during antithrombotic therapy, the BP at admission was related to the patients functional outcomes (p<0.1). In conclusion, BPs during the acute phase were associated with the functional outcomes at discharge of ICH patients.
