Abstract
Background and Purpose: Moyamoya disease has been studied concerning its natural history and treatment. Japanese guidelines for Moyamoya disease were suggested on 2009. We studied the outcome of initial and recurrent patients with Moyamoya disease in our institute.Methods: Between 1982 and 2012, we analyzed the follow up reports on 49 consecutive patients including 37 initial patients and 12 recurrent patients.Results: Twenty-seven patients presented with ischemic disease, and 10 presented with hemorrhagic disease. In the initial treatment group, higher age patients presented with hemorrhagic disease, and poorer prognosis compared with younger patients. In the recurrent group, almost all patients presented hemorrhagic disease, and poorer prognosis compared with the patients of initial group. The ischemic group of patients, treated with surgical anastomosis, presented with a lower recurrence rate.Conclusions: Our study suggests that Moyamoya disease frequently presented with hemorrhagic disease at recurrence, and that surgical anastomosis for ischemia at the initial hospitalization has a possibility of prevention of recurrent cerebrovascular events.
