Neuroprotection for ischemic stroke

Abstract

Neuroprotective therapy with edaravone does not protect only neural cells but also the neurovascular unit as a whole. Therefore, this therapy greatly reduces hemorrhagic transformation under thrombolytic therapy with tPA or endovascular surgery in acute stroke. Recent reports showed an improving recanalization rate in tPA therapy. The neuroprotective drug edaravone is currently used in daily stroke clinics of Japan, China and India. A recent report from Europe displayed similar protective results in their countries with edaravone.