2018 Volume 40 Issue 1 Pages 7-10
Background and Purpose: We investigated whether the background factors of patients with bilateral “Champagne bottle neck sign (CBNS)” are different from those with unilateral CBNS. Methods: The subjects were 26 patients with CBNS demonstrated by carotid ultrasonography, who received brain MRI. The CBNS was noted unilaterally in 13 patients and bilaterally in the other 13. We compared between the two groups of incidence of atherosclerotic risk factors, carotid plaque on ultrasonography, and brain MRA findings that were characteristic of moyamoya disease or atherosclerosis. Results: The prevalence rates of hypertension, dyslipidemia, and plaque at the carotid arteries were higher in the unilateral group than in the bilateral group significantly (p=0.03). The MRA findings of moyamoya disease were more frequently seen in the bilateral group than in the unilateral group (46% vs. 100%, p<0.001) and that of atherosclerotic disease was seen in 46% of the unilateral group but not in the bilateral group (p<0.001). Conclusions: It seems that bilateral CBNS is strongly related to moyamoya disease and the unilateral CBNS is not only to moyamoya disease but also to atherosclerosis.
