2020 Volume 42 Issue 2 Pages 80-83
Purpose and Method: We investigated prothrombin time (PT) and activated partial thromboplastin (APTT) tests using two different reagents and the relationship between PT and APTT and anti-factor Xa activity (AXA) in patients treated with edoxaban. Results: Two reagents had the high correlation with PT (R =0.95, p<0.001), but not APTT (R =0.55, p =0.001). AXA provided the correlation with both PT tests. However, APTT was different between the two reagents. One reagent did not have the relationship between APTT and AXA. Conclusion: In clinical practice, PT test was suggested to be better to estimate the drug effects for edoxaban if AXA was available.
