Sarcopenia in acute ischemic stroke patients

Abstract

Background and Purpose: The aim of this study was to investigate the serial changes in skeletal muscle mass and actual state of sarcopenia in acute ischemic stroke patients. Methods: Between January 2019 and September 2020, we enrolled 101 ischemic stroke patients admitted within 48 hours of onset. Measurement of skeletal muscle mass was performed on admission and 2 weeks after admission (follow-up). Handgrip strength and gait speed were assessed at follow-up. The frequency of sarcopenia and its associated factors were retrospectively investigated. Results: Sarcopenia was identified in 58 patients (57%). Of these, only 3 patients developed low skeletal muscle mass during hospitalization. Multivariate logistic regression analysis showed that age (OR 1.2, 95%CI 1.060–1.267), body mass index (OR 0.7, 95%CI 0.526–0.881), and Food Intake LEVEL Scale (OR 0.3, 95%CI 0.117–0.841) were independent factors associated with sarcopenia. Conclusion: There were a few patients who developed low skeletal muscle mass during hospitalization.