Japanese Journal of Stroke
Online ISSN : 1883-1923
Print ISSN : 0912-0726
ISSN-L : 0912-0726
Case Report
A Case of Reversible Cerebral Vasoconstriction Syndrome Associated with Basedow’s Disease
Naoki Hayashi , Natsuka Mizutani, Rika Shibano, Ryo Morikawa, Takafumi Oguri, Yuhi Fukanuma, Koji Matsuo, Hisayoshi Niwa
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JOURNAL OPEN ACCESS

2026 Volume 48 Issue 3 Pages 126-133

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Abstract

A 48-year-old woman developed headache and severe visual disturbance upon waking up. On arrival at our hospital, the patient was completely blind and had mild left-lower-limb paralysis. Diffusion-weighted brain magnetic resonance imaging revealed high-signal-intensity lesions in the bilateral occipital lobes, and a FLAIR high ventral pontine lesion was observed. Brain MRA revealed spasms in all cerebral arteries. We suspected reversible cerebral vasoconstriction syndrome and stroke, so the patient was treated with edaravone, lomerizine, and aspirin. Then, we treated the patient for Basedow’s disease. Brain imaging indicated worsening until the fifth day of illness but gradual improvement along with her neurological symptoms. On day 35 of hospitalization, her left-sided paralysis healed, and her vision returned to the manual valve level. Five months after onset, her visual acuity was 0.3, and she was able to perform independently at home. Basedow’s disease may induce spasms in the cerebral arteries.

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© 2026 The Japan Stroke Society

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https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ja
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