Abstract
We had five cases with intracranial hemorrhage occured during long-term oral anticoagulant drug therapy (particularly warfarin therapy).
Intracranial hemorrhages comprised chronic subdural hematoma in 4 cases and subcortical hematoma in 2 cases, including one case chronic subdural hematoma following subcortical hematoma five years later.
Surgical management was performed upon discontinuing and neutralyzing warfarin by Vitamin K at that period of diagnosis, raising thromb-test over 50%. The interval of discontinuing warfarin was 1-3 weeks postoperatively, examining blood coagulating system and no case had bleeding tendency nor cerebral embolus except for one case with a bleeding episode postoperatively.
Management of intracranial hemorrhage occured during long-term anticoagulant drug therapy, including chronic subdural hematoma and subcortical hematoma which indicate good prognosis, should be carried out surgically, discontinuing, neutralyzing anticoagulant drug and controlling blood coagulating factors.
