Abstract
In order to investigate the changes of regional cerebral blood flow (rCBF) by the cold pressor test (CPT), it was carried out to 46 patients with cerebral thrombosis and 33 patients with cerebral hemorrhage in chronic stage, and to 16 cases with non-cerebrovascular disease.
After 15 min rest, rCBF on the affected side of the hemisphere was measured by the infusion method of 133Xe into internal carotid artery. According to the mean of rCBF (m-rCBF), all of subjects with stroke were classified into 3 groups, namely, group I; m-rCBF≥40 ml/100 g/min, gruop II; 40 ml/100 g/min>m-rCBF≥30 ml/100 g/min, group III; 30 ml/100 g/min>m-rCBF.
Results were as follows.
1) Systolic blood pressure, diastolic blood pressure and heart rate increased clearly after the CPT in all of subjects.
2) m-rCBF of group III in the cerebral thrombosis and the cerebral hemorrhage increased markedly after the CPT. And also, autoregulation index of group III in the cerebral thrombosis was higher than those in other groups.
3) m-rCBF of group I in the cerebral hemorrhage decreased after the CPT, however in the cerebral thrombosis did not.
These results suggest that m-rCBF in the patients of lower cerebral blood flow with stroke is apt to increase by the cold stress, and the autoregulation in those patients with cerebral thrombosis disorders more.
