Japanese Journal of Stroke
Online ISSN : 1883-1923
Print ISSN : 0912-0726
ISSN-L : 0912-0726
Ovarian hyperstimulation syndrome and cerebral infarction
Hiromichi TanakaSatoko DoiJun SaitouHiroshi KagimotoHiroki Fukuda
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1997 Volume 19 Issue 1 Pages 79-83

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Abstract
A 30-year-old woman, on hMG-hCG therapy for sterility, was referred to our hospital because of sudden onset of confusion and left hemiplegia. Her family members reported that abdominal distension and oliguria had appeared several days before. She was mute and restless, with concurrent enlarged ovaries and ascites. MRI revealed an extensive infarction in the territory of the right middle cerebral artery (MCA) and an infarction in the left temporal cortex. MR angiography (MRA) performed at 57 days after the onset demonstrated a patent MR portion and an occluded M2 portion in the right MCA. On admission, thrombin-antithrombin III complexes and D-dimer were increased. The sudden onset of symptoms and MRA findings suggested embolic infarction, probably caused by hypercoagulability due to ovarian hyperstimulation syndrome.
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