Abstract
A 59-year-old right-handed woman was admitted to our hospital because of left hemiparesis. On the second day brain CT revealed right striatocapsular infarction and bilateral temporoocipital infarction. Electrocardiography, and transthoracic and transesophageal echocardiography showed no abnormalities. On the second day, cerebral angiography disclosed stenosis of the bilateral middle cerebral arteries. Antithrombotic therapy was started under a diagnosis of cerebral infarction associated with essential thrombocythemia. Follow-up cerebral angiography on the 9th day revealed disappearance of the stenotic lesions of the bilateral middle cerebral arteries This patient represents a rare case with disappearance of thrombotic stenosis of the bilateral middle cerebral arteries associated with essential thrombocythemia following antithrombotic therapy.