Abstract
To clarify the possible usefulness of Japan Stroke Scale (JSS), we applied this scale to acute ischemic stroke patients and compared with the Hemispheric Stroke Scale (HSS) as physical deficit scale and the Barthel Index (BI) as functional scale. Forty-seven patients with acute (<3 days) ischemic stroke were included. The rating scale was tested before and 1, 3, 7, 14 and 28 days after the treatment. The JSS score correlated well with the HSS (r=0.92) and the BI score (r=-0.80). The JSS and HSS scores were significantly decreased with the process of time. Significant decrease in the JSS score was found at 3 days after the treatment, while the HSS score was not significantly changed until 7 days after treatment. Both groups treated with argatroban and with ozagrel Na showed significant decrease in the JSS and the HSS scores, although there wan no significant difference in the rate of score reduction with the process of time between the two treatment groups. The JSS should prove useful in quantifying neurologic deficits in ischemic stroke and in following changes in neurological status.