Abstract
Seven patients with megadolicho anomaly were studied for the complication of cerebral infarction. Cerebral infarction was diagnosed in 6 of them, mainly lacunar infarction, by CT or autopsy. They tended to be hypertensive, younger in age of onset than patients without megadolicho anomaly and have a stepwise deterioration of neurological deficits. As to the cause of the high frequency of lacunar infarction in patients with megadolicho anomaly, the decrease of “Windkessel function” due to the absence of elasticity of the seemed to accelerate the arteriosclerotic changes at the perforating arteries associated with lacunar infarctions. Therefore, it was suggested that non-stenotic arteriosclerotic changes of the main trunk induced lacunar infarction because of the reduction of “Windkessel function”.
