Abstract
This is to report on the 9 autopsy cases clinically observed by Sano et al. Grossly, in all cases homorrhagic pneumonia was observed in both sides and in all lobes of the lung, showing the appearance of socalled splenization. No pleurisy was observed. Bleeding was found the serosa of all bodily cavities, in the mucosa of alimentary canals and in the retroperitoneum etc. The leptomeninx was congested and slightly turbid, in 4 cases the spleens were slightly enlarged and in 7, we observed hemorrhagec erosion in the stomachs.
Histological examinations: In the affected part of the lung the alveolar septa were often greatly distended owing to excessive blood congestion and cellular infiltration, giving the appearance of interalveolitis. The infilitrating cells mainly consisted of medium-sized mononuclear cells and cells with oblong nuelei, mingled with a small number of leucocytes. Edema, atelectasis and emphysema were found scattered in disorder among the area of hemorrhages and interalveoritis. In some part desquamation of the bronchiolar epithelium was visible, but no necrotic and degenerative change was found, except a case in which klebsiella pneumoniae was discovered from the lung. No hyaline membrane was found on the surface of alveoli and bronchioli, nor any hyaline thrombus in the capillaries. Fibrin and swallowed epithelium were occasionally found in the air sacs. In spite of hard investigation, no inclusion bodies could in the bronchial and alvleolar epitheliums. Beside the above, hepatitis, serous hepatitis, light leptomeningitis and occasionally nephrosis were observed.
