Abstract
The inhibitory effect of homosulfamin on the intracellular phage growth was investigated here, with respect to the determination of the sensitive part of the phage multiplication course. The latent period of T4r phage was divided, at least, into three distinct stages as to homosulfamin-sensitivity, i.e., the first insensitive stage (first 6 minutes), the second complete sensitive stage (6 to 15 or 16 minutes), and the third or final insensitive stage (16 to 20 minutes), and concluded that this drug may attack some essential reactions relating to either synthesis of virus DNA or the synthesis process of the virus particles from their precursors.
The drug action was analysed from chemical kinetic point of view, and 50 per cent inhibition does on bacterial and virus growth were 0.18 and 0.29 per cent, respectively.
