Abstract
I. Brain and spinal cord of mouse infected and paralyzed with poliomyelitis virus Lansing strain were inserted into bananas and were orally administered to 9 cynomolgus monkeys. Tokyo strain virus (type 2) was also administered to 6 monkeys in the same way. None of of all the 15 monkeys manifested the signs of apparent infection by the oral administration of the virus.
II. Viremia was recognized on 6 of 15 monkeys during the period ranging from the very day of the virus administration to 4-5 days after it. Also of 3 among 7 groups the viruses were positive in stool specimens only on the next day of the virus administration.
III. Two monkeys which had inoculated with cow serum γ-globulin were both viremia negative, and their stool specimens were also virus negative.
IV. Noticable increase of neutralizing antibody of the monkey sera was not observed after the oral administration of the viruses.
