Abstract
The susceptibility to virus should be reconsidered by the specificity of virus different from other bacteria. By conducting a study on the effect of Cortisone on the susceptibility of mice to virus, I have confirmed that the administration of Cortisone increases the susceptibility of mice to the mouse encephalomyelitis virus (GDV11 strain). For this purpose it is necessary to administer comparative large doses of Cortisone before inoculation of virus. On that occasion the effect of Cortisone in the groups of intraperitoneal or subcutaneous inoculation of virus is more significant than that in the groups of intracerebral or intranasal inoculation.
This experiment is thought to be suitable for analytic study on the problems of susceptibility to virus. The essential of this effect will be reported on later date.