Abstract
In smear preparations of vaccinia virus inoculated on rabbit cornea or on the chick chorioallantoic membrane, I have found that with the Giemsa stain two types of inclusion body can be observed. One is a pale blue staining inclusion body, the “A” type inclusion body and the other a red staining inclusion body, the “B” type inclusion body or the so-called Guarnieri body.
The Guarnieri body seen in section preparation is identical with the pale blue staining “A” type inclusion body seen in Giemsa stained smear preparations. Therefore there are two types of inclusion bodies that are called Guarnieri body.
The “B” type inclusion body of the vaccinia virus is morphologically and in developmental procedure, very similar to the “B” type inclusion body of ectromelia virus and fowlpox virus. The “A” type inclusion body, however, in comparison to the “A” type inclusion bodies of ectromelia and fowlpox virus is seen less frequently.
