Abstract
Persistent left cranial vena cava with defect of right cranial vena cava was diagnosed pathologically in a 6-year-old male Shetland sheep dog suffering from heartworm disease and renal failure. Only one heartworm was surgically removed from the dog through the jugular vein. The examination of cardioangiography indicated the unusual cranial vena cava, though definitive diagnosis could not be made. The dog died on day 340 despite fluid therapy and medical treatment with trapidil, aspirin and aminophyline. Left cranial vena cava was found at necropsy, whereas no remnants of the right cranial vena cava was observed. No cardiovascular anomalies were detected.