Vectorcardiographic Study on Cardiac Hypertrophy in SHR (McFee-Parungao Lead System)

Tomoe MIYAZAWA; Sadayuki SATO; Souichiro SEKIYA; Takeshi TSUTSUMI; Hirofumi OSADA

doi:10.11276/jsvc1984.18.35

Tomoe MIYAZAWA, Sadayuki SATO, Souichiro SEKIYA, Takeshi TSUTSUMI, Hirofumi OSADA

Author information

JOURNAL FREE ACCESS

1985 Volume 18 Issue 18 Pages 35-42

DOI https://doi.org/10.11276/jsvc1984.18.35

Details

Published: 1985 Received: - Available on J-STAGE: September 17, 2009 Accepted: - Advance online publication: - Revised: -
Correction information
Date of correction: September 17, 2009 Reason for correction: - Correction: CITATION Details: Wrong : 4) YAMORI, Y. (1974): Contribution of cardiovascular factors to the development of hypertension in spontaneously hypertensive rats: A preliminary report. Jpn. Heart J. 15:194-196.
5) YAMORI, Y., OHTAKA, M. and NARA, Y. (1976): Vectorcardiographic study on left ventricular hypertrophy in spontaneously hypertensive rats. Jpn. Circ. J. 40:1315-1329.
6) OHTAKA, M. (1980): Vectorcardiographical and pathological approach to the relationship between cardiac hypertrophy and coronary arteriosclerosis in spontaneously hypertensive rats (SHR). Jpn. Circ. J. 44:283-293.
9) CHO, T. C., HEIM, R. A. and KAPIAN, S. (1974): Clinical vectorcardiography, 2nd ed., Grune and Stratton, New York.
10) MCFEE, R and PARUNGAO, A. (1961): An orthogonal lead system for clinical electrocardiography. Am. Heart J. 62:93-100.
14) DRISCOLL, P. (1981): The rat electrocardiogram in pharmacology and toxicology. Edited by BUDDEN, R., DETWEILER, D. K. and ZBINDEN, G. Pergamon Press, Oxford.
15) BEINFIELD, W. H. and LEHR, D. (1968): Q RS-T variation in the rat electrocardiogram. Am. J. physiol. 214:197-204.
16) MCFEE, R. and JOHNSTON, F. D. (1953): Electrocardiographic lead. I. Introduction. Circulation 8:554-568.
17) MCFEE, R. and JOHNSTON, F. D. (1954): Electrocardiographic lead. II. Analysis. Circulation, 9:255-266.
18) MCFEE, R. and JOHNSTON, F. D. (1954): Electrocardiographic leads. III. Synthesis. Circulation, 9:864-880.
19) SNOECK, J., WITTESAELE, W., VANAGT, E. and VRINTS, C. (1982): Evolution of left ventricular hypertrophy and orthogonal-vectorcardio-graphic parameters in S. H. R. Jpn. Heart J. 23:477-479.
20) BENCHIMOL, A. (1974): Vectorcardiography. The Williams and Wilkins Company, Baltimore.
21) HODGKIN, B. C., NELSON, C. V. and ANGELAKOS, E. T. (1981): Cardiac electrical resultant dipole moment of spontaneously hypertensive rats. Am. J. Physiol. 214:H541-H546.

Right : 4) YAMORI, Y. (1974): Contribution of cardiovascular factors to the development of hypertension in spontaneously hypertensive rats: A preliminary report. Jpn. Heart J. 15:194-196.
5) YAMORI, Y., OHTAKA, M. and NARA, Y. (1976): Vectorcardiographic study on left ventricular hypertrophy in spontaneously hypertensive rats. Jpn. Circ. J. 40:1315-1329.
6) OHTAKA, M. (1980): Vectorcardiographical and pathological approach to the relationship between cardiac hypertrophy and coronary arteriosclerosis in spontaneously hypertensive rats (SHR). Jpn. Circ. J. 44:283-293.
9) CHO, T. C., HEIM, R. A. and KAPIAN, S. (1974): Clinical vectorcardiography, 2nd ed., Grune and Stratton, New York.
10) MCFEE, R and PARUNGAO, A. (1961): An orthogonal lead system for clinical electrocardiography. Am. Heart J. 62:93-100.
14) DRISCOLL, P. (1981): The rat electrocardiogram in pharmacology and toxicology. Edited by BUDDEN, R., DETWEILER, D. K. and ZBINDEN, G. Pergamon Press, Oxford.
15) BEINFIELD, W. H. and LEHR, D. (1968): QRS-T variation in the rat electrocardiogram. Am. J. physiol. 214:197-204.
16) MCFEE, R. and JOHNSTON, F. D. (1953): Electrocardiographic lead. I. Introduction. Circulation 8:554-568.
17) MCFEE, R. and JOHNSTON, F. D. (1954): Electrocardiographic lead. II. Analysis. Circulation, 9:255-266.
18) MCFEE, R. and JOHNSTON, F. D. (1954): Electrocardiographic leads. III. Synthesis. Circulation, 9:864-880.
19) SNOECK, J., WITTESAELE, W., VANAGT, E. and VRINTS, C. (1982): Evolution of left ventricular hypertrophy and orthogonal-vectorcardiographic parameters in S. H. R. Jpn. Heart J. 23:477-479.
20) BENCHIMOL, A. (1974): Vectorcardiography. The Williams and Wilkins Company, Baltimore.
21) HODGKIN, B. C., NELSON, C. V. and ANGELAKOS, E. T. (1981): Cardiac electrical resultant dipole moment of spontaneously hypertensive rats. Am. J. Physiol. 214:H541-H546.

Abstract

To examine vectorcardiography of left ventricular hypertrophy (LVH) in a spontaneously hypertensive rat (SHR), vectorcardiogram (VCG) was recorded from ten 30-week-old SHRs and ten age-matched Wistar rats (WR) by applying McFee-Parungao lead system for the dog.
Arterial blood pressure (BP) was 113.25±11.83mmHg in WR and 188.43±19.17 mmHg in SHR. VCG was recorded by McFee-Parungao lead system in restrained ventral position after being anesthetized with urethan-chloralose. VCG was measured on the following parameters; orientation, magnitude and time of maximum QRS vector (Max QRSv), orientation and magnitude of maximum T vector (Max Tv), QRS-T angle and ratio of T/QRS.
VCG in SHR was characterized by superior, posterior and leftward shift of QRS loop, prolongation of time of Max QRSv, and an increase of QRS-T angle in all planes. These observations of VCG in SHR were very similar to those of LVH due to pressure overloading in humans.

Corresponding author

Correction information

Register with J-STAGE for free!