2017 Volume 26 Issue 3 Pages 153-156
We report a case of critical limb ischemia in a 72-year-old man with essential thrombocythemia (ET) who was treated with hydoroxycarbamide. He came to our hospital due to necrosis of his right toe. Angiography demostrated occlusion of the right anterior tibial artery, the peroneal artery, and the plantar artery. We planned bypass surgery after the optimal control of the platelet count. However, necrosis progressed rapidly, we performed femorodistal bypass using an autologous vein graft despite of poor platelet control. After the operation, antiplatelet agents (aspirin and clopidgrel) and anticoagulants (apixaban and heparin) in addition to hydroxycarbamide were useful for ET patients to prevent graft thrombosis.
