Abstract
The patient was a 41-year-old woman who presented to our hospital with persistent left inguinal pain that had not been diagnosed for >2 years. Diagnostic work-up (including ultrasonography and computed tomography) revealed a left inguinal mass, which appeared to be the cause of her symptom. As definitive diagnosis and treatment, she underwent surgical resection. Under general anesthesia, the left groin was opened and the mass was found in the common femoral vein. En bloc resection of the mass and a part of the common femoral vein was performed, and the greater saphenous vein was mobilized and transposed onto the distal femoral vein using the modified May-Husni technique. Histologically, the tumor originated from the common femoral vein, and consisted of the tumor cells with some epithelioid morphologies. Immunohistological staining demonstrated that the tumor cells were positive for several endothelial markers (such as CD31, CD34 and ERG) and negative for other types of tumor markers. Moreover, the cells were positive for CAMTA1, which strongly suggested the presence of the WWTR1-CAMTA1 fusion gene. These microscopical findings were characteristic of epithelioid hemangioendothelioma. Postoperatively, the patient has been doing well for a year without obvious signs of tumor recurrence.
