Abstract
We report a case of acute interstitial nephritis after endovascular repair for a ruptured infected abdominal aortic aneurysm. A 67-year-old man had surgery for gastric cancer. Two months after the operation, the patient had an unconsciousness attack with decline of blood pressure. Laboratory data showed significant inflammation, and CT scan revealed an infected abdominal aortic aneurysm with a hematoma in the retroperitoneal space. He was diagnosed as a ruptured infected abdominal aortic aneurysm and underwent emergent endovascular repair using Gore Excluder®. Antibiotics including β-lactam were administered to cover a wide range of bacteria. Renal function gradually worsened and white blood cell count rose with a high ratio of eosinophils. It was suspected that the patient developed acute interstitial nephritis caused by β-lactam antibiotics. Even though temporary hemodialysis was needed, renal function gradually improved after discontinuation of β-lactam antibiotics and administration of steroids. The patient was discharged on the 40th postoperative day, and has remained asymptomatic for 1 year after surgery.