Abstract
The removal of pharmaceuticals in the membrane separation bioreactor process was examined. The deposition of activated sludge on the microfiltration membrane surface provided an additional barrier for the permeation of target substances, although the additional effect of the deposition on the removal was lower than 25% for hydrophilic compounds with log Kow between 2 and 3. The additional effect increased with time and log Kow, and reached 65% after 44 days of operation for a solute with a log Kow of 4.8.