Abstract
Over the last two decades, the incidence of allergic patient has been risen worldwide. Which much effort has been paid to develop a new anti-allergic drug, allergic disease has not yet been completely conquered. Drug development for allergic disease has been directed at improving existing agents and expanding new modalities that target the allergic inflammation.
Both strategies are important to develop a new anti-allergic drug, one more important study is to elucidate the scientific mechanism of the efficacy of traditional Chinese medicines which are using for treatment of allergic diseases in Japan. In this manuscript, our studies on anti-allergic action of natural products and crude extract of herbal medicine or traditional Chinese medicine are described.