Journal of Traditional Medicines
Online ISSN : 1881-3747
Print ISSN : 1880-1447
ISSN-L : 1880-1447
Review
Metabolic activation of lignans to estrogenic and antiestrogenic substances by human intestinal bacteria
JiangJing GAOMasao HATTORI
Author information
JOURNAL RESTRICTED ACCESS

2005 Volume 22 Issue 4 Pages 213-221

Details
Abstract
The role of human intestinal bacteria is indispensable for the metabolic activation of phytoestrogenic precursor lignans. This review summarized recent researches on the in vitro intestinal bacteria transformation of lignan precursors, secoisolariciresinol diglucoside (SDG), arctiin, pinoresinol diglucoside (PDG), and their aglycones, to mammalian lignans enterodiol (END) and enterolactone (ENL). The isolation and characterization of several bacteria from human feces, responsible for the related reactions were also described.
Content from these authors
© 2005 Medical and Pharmaceutical Society for WAKAN-YAKU
Next article
feedback
Top