Hangekobokuto (Ban-Xia-Hou-Po-Tang), a Kampo medicine, decreases brachial-ankle pulse wave velocity

Hidenori ITO; Yoshitaka YONETA; Tetsuro OIKAWA; Hiroshi ODAGUCHI; Akino WAKASUGI; Hisakazu SHODA; Takayuki HOSHINO; Koji WATANABE; Yuji GAMO; Toshihiko HANAWA

doi:10.11339/jtm.23.173

Regular Article

Hangekobokuto (Ban-Xia-Hou-Po-Tang), a Kampo medicine, decreases brachial-ankle pulse wave velocity

Hidenori ITO, Yoshitaka YONETA, Tetsuro OIKAWA, Hiroshi ODAGUCHI, Akino WAKASUGI, Hisakazu SHODA, Takayuki HOSHINO, Koji WATANABE, Yuji GAMO, Toshihiko HANAWA

Author information

Hidenori ITO
Oriental Medicine Research Center of the Kitasato Institute
Department of Oriental Medicine, Doctoral Program of Medical Science, Kitasato University, Graduate School of Medical Science
Yoshitaka YONETA
Oriental Medicine Research Center of the Kitasato Institute
Tetsuro OIKAWA
Oriental Medicine Research Center of the Kitasato Institute
Hiroshi ODAGUCHI
Oriental Medicine Research Center of the Kitasato Institute
Department of Oriental Medicine, Doctoral Program of Medical Science, Kitasato University, Graduate School of Medical Science
Akino WAKASUGI
Oriental Medicine Research Center of the Kitasato Institute
Department of Oriental Medicine, Doctoral Program of Medical Science, Kitasato University, Graduate School of Medical Science
Hisakazu SHODA
Oriental Medicine Research Center of the Kitasato Institute
Department of Oriental Medicine, Doctoral Program of Medical Science, Kitasato University, Graduate School of Medical Science
Takayuki HOSHINO
Oriental Medicine Research Center of the Kitasato Institute
Department of Oriental Medicine, Doctoral Program of Medical Science, Kitasato University, Graduate School of Medical Science
Koji WATANABE
Oriental Medicine Research Center of the Kitasato Institute
Department of Oriental Medicine, Doctoral Program of Medical Science, Kitasato University, Graduate School of Medical Science
Yuji GAMO
Oriental Medicine Research Center of the Kitasato Institute
Department of Oriental Medicine, Doctoral Program of Medical Science, Kitasato University, Graduate School of Medical Science
Toshihiko HANAWA
Oriental Medicine Research Center of the Kitasato Institute
Department of Oriental Medicine, Doctoral Program of Medical Science, Kitasato University, Graduate School of Medical Science

Keywords: Hangekobokuto, brachial-ankle pulse wave velocity, vascular wall tone, sympathetic nervous system

JOURNAL FREE ACCESS

2006 Volume 23 Issue 5 Pages 173-177

DOI https://doi.org/10.11339/jtm.23.173

Details

Abstract

We investigated the effect of Hangekobokuto (Ban-Xia-Hou-Po-Tang ; HKT) by brachial-ankle pulse wave velocity (baPWV) measurement. HKT was prescribed to 21 patients. In the HKT group, baPWV decreased significantly after a 6-month continuous prescription without change in pulse rate, blood pressure and ankle brachial index. But in Hachimijiogan (Ba-Wei-Di-Huang-Wan) group as compared with the HKT group, there was no significant change of baPWV or other parameters. These results suggest that HKT brings about functional change in vessels rather than organic change; that is, HKT decreases latent vascular wall tone, which is closely related to the autonomic nervous system.

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