Effect of Fuscoporia obliqua with exercise on blood glucose and lipid in type 2 diabetic mice

Abstract

The effect of Fuscoporia obliqua (Fuscoporia Murr.) was investigated on KK-Ay exercised mice, an animal model with type 2 diabetes with hyperinsulinemia. A water extract of Fuscoporia obliqua (FO) with exercise reduced the blood glucose of KK-Ay mice after a single oral administration. FO with exercise reduced the blood glucose of KK-Ay mice, and also significantly lowered the plasma triglyceride of KK-Ay mice 3 weeks after repeated oral administrations. The plasma triglyceride of FO with exercise is lower than that of exercise only 3 weeks after the administration. These results suggest that FO with exercise is useful for a type 2 diabetic treatment.