1996 Volume 13 Pages 27-34
Borep peptide (B) (made from the globin protein of bovine red blood cell) and whey peptide (W) (made from whey protein) have been reported about the function to regulate the fat metabolism. Borep (B) improved the serum tria:cylglycerol and whey peptide (W) depressed the serum total cholesterol.
Taurine in the oyster extract (O) improve the cholesterol metabolism in serum and liver.
We have studied about the influence of the oligopeptide (B and W) and oyster extract (O) on the lipid metabolism in rats. Normal diet and high fat diet were fed to 2 groups of Wistar male rats. After 4 weeks, the diet of high fat diet group was changed to normal diet (HC group). We added the Borep (B), whey peptide (W) and oyster extract (O) with various combinations to HC diet, i.e. HC, HC+O, HC+B, HC+W, HC+O+B and HC+O+B+W groups. After breeding each group for 4 weeks, we took the serum and analyzed the total cholesterol and triacylglycerol of them.
Comparing with HC group, total Cholesterol (TC) of the HC+W group was slightly decreased and triacylglycerol (TG) of the HC+B group was also slightly decreased in the carotid and peripheral serum. But carotid serum TG of HC+O group significantly decreased, though peripheral serum TC of HC+O slightly decreased. In the liver of HC+O group, TC and TG decreased. Comparing the HC+B group, TC and TG in the carotid and peripheral serum slightly decreased. And in the HC+O+B+W group, carotid TG decreased compared with other groups.