1999 Volume 16 Pages 125-130
Oyster extracts contain important trace nutrients such as taurine and zinc abundantly, and that it has various physiological function such as platelet aggregation inhibitory function or blood glucose improvement effect is reported . Further, antioxidative activity of oyster extracts has been confirmed using model system.
In this study, we examined the effect of oyster extracts supplementation on oxidizability of rats plasma and red blood cells (RBC) membrane. Rats were fed AIN93G diet containing oyster extracts (0.5, w/w) for 5 weeks. The oxidizability of plasma and RBC membrane, as evaluated in vitro by the duration of the lag-phase in hemin-hydrogen peroxide induced oxidation, were significantly decreased. In addition, the total antioxidative activity were significantly increased. On the other hand, a major antioxidative substances and peroxidizability index in plasma and RBC membrane were not changed by oyster extracts supplementation. These results suggest that a certain factors, such as polyphenol, flavonoid, play an important role in antioxidative effects of oyster extracts supplementation.