2001 Volume 18 Pages 47-51
To clarify effects of over dose or under dose of calcium intake in mature female rats were studied. Wistar mature female rats, over 25-wk-old, multipara (over 4 paras), were divided into five groups and diets of different amount of calcium ; (1) Ca 1/10 times, (2) Ca 1 times (control), (3) Ca 2 times, (4) Ca 5 times, (5) Ca 10, times were given for 4 weeks. Hematological parameters and biochemical parameters in plasma were monitored. ALP levels significantly decreased in the rats fed with low Ca diet (Ca 1/10) compared to in control rats. GOT, GPT and UN levels significantly increased in the rats fed with high Ca diet (Ca 10) compared to in control rats. TIBC levels significantly decreased in the rats fed with high Ca diet (Ca 5, Ca 10) compared to in control rats. These results suggest that not only low intake of Ca but over intake of Ca is fallen into ill health.
