Effects of Chicken Extract and Peptides for the Gastric Secretion in Rats

Abstract

Iron is an essential element for all living organisms, and is a key functional component of oxygen transporting and storage molecules and of many enzymes. It is well established that the bioavailability of non-heam iron from foods is enhanced by the presence of meat. However, the factor associated with improving iron absorption in meat has yet to be identified. Thus, we determined the gastric secretion in pylorus-ligated rats administered Chicken Breast Extract (CBEX, Nippon Meat Packers, Inc.) and peptides.

The rats administered CBEX had significant increased pepsin activity and pepsin output compared with the control rats. There was no significant difference in gastric juice pH between the control and CBEX-administered rats. Furthermore, the carnosine-administered rats exhibited significant increases in pepsin activity and pepsin output. On the other hand, no significant differences in pepsin activity and pepsin output were observed between the control and taurine-administered rats. These results indicate that CBEX and carnosine decrease pH in the stomach by enhancing pepsin activity and pepsin output.