1986 Volume 3 Pages 61-68
The effects of dietary oyster extract on platelet aggregation were investigated. The inhibition effects of oyster extract was found in Wister male rat platelet aggregation in vivo as well as human platelet aggregation in vitro.
Effects of oyster extract was investigated in alloxan diabetes rat. These animals were fed on different oyster level (20mg/kg/day, 200mg/kg/day) diet for 3 weeks. A remarkable improvement of platelet aggregation and blood glucose levels was obserbed.
The taurine and zinc (Zn2+) contents in oyster extract show high level (12.7g/100g, 61.0mg/100g, respectively). Three group animals were fed on component of oyster (1. Taurine, 2. Zinc chloride, 3. Taurine and zinc chloride) added diets for 3 weeks. No significant change was obserbed in platelet aggregation and glucose tolerance test. It was not affected in addition of the component of oyster, but was very effective in administration of oyster extract. From the above results, it is suggested that effects of oyster extract against alloxan diabetes and platelet aggregation is based on potentiation by components of oyster extract.
