2018 Volume 35 Pages 1-5
Oyster (Crassostrea gigas) contains abundant nutrients, including glycogen, vitamins, zinc and taurine. It is reported that Oyster extract exhibited anti-oxidative effect, anxiolytic-like effects and several physiological activities in mice.
In this pilot study using three male cynomolgus monkeys (Macaca fascicularis), we reported evaluation of effect of oyster extract on stress in cynomolgus monkey by analysis of blood glucose, serum cortisol, serum DHEA and serum adrenalin levels.
Oyster extract administrated. After 7 days of administration of test substance, light-stress was induced and the stress marker was measured.
The number of monkeys used for the experiment was three and the statistical inference was not performed. There were no difference in blood glucose and DHEA level between control group and oyster extract. Oyster extract group had lower serum cortisol level in the endocrine system of the stress transmission, than control group. In serum adrenaline level in the autonomic nervous system of the stress transmission pathway, control group rapidly increased 2 hours after administration. However, oyster extract had only a moderate rise.
Because the outcomes of the study were tentative and exploratory, any conclusion cannot be advocated until further confirmatory study.
