The Effect of Calcium Administration on Restrain Stress

Abstract

Stress is a condition in which strain appears in the body due to some external stimulus inflicted on the body. The external stimulus is called the stressor and produces an abnormality of homeostasis in the living body. Stress participates in both the genesis of arteriosclerosis and changes in the calcium dynamic in the body. A study investigating the effect of calcium administration on stress and arteriosclerosis was perfomed.

In this experiment, six-week old male Wistar rats were for six weeks with a calcium-supplementaled feed. After this phase, restraint stress was applied for 12 hours and a macroscopic study was performed in organs and blood components.

The results of this study disclose an inhibition of the serum aldosterone rise in the calcium administration group and blood cell serotonin decrease which is usually seen in response to restraint stress. However, the difference in serum calcium was small. Atrophy of the thymus and spleen was inhibited in the calcium administration group as compared with controls. This preliminary data appears to demons- trate an effect of calcium administration on the physiologic stress response.